‹ ›
MYP_102007
← PREVIOUS NEXT → BACK
Basic Information
Temporin-1Vc
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
13 amino acids
C75H122N14O15S
Standard
Sequence
FLPLVTMLLGKLF
Physicochemical Analysis
1491.92 Da
8.75
0.76
0.55
0.0584
1.85
0.32
0.65
4.45
172.31
0.1538
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
449.98
1.99
15.0
17.0
47.0
105.0
3.0
12.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0003123 VERIFIED: YES
Provenance & Taxonomy
Rana virgatipes [Animal]
Temporin
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Amidation
C-terminal amidation
Bio-Activity Profile
Antimicrobial
Staphylococcus epidermidis RP62A
10 μM
MIC
PaperPurification and characterization of antimicrobial peptides from the skin secretions of the carpenter frog Rana virgatipes (Ranidae, Aquarana).
RECORD: Rec_0015950 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0065830 VERIFIED: YES
Provenance & Taxonomy
Rana virgatipes [Animal]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus NCTC8325
5 μM
MIC
PMID15996769 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15996769/
RECORD: Rec_0076681 VERIFIED: YES
Provenance & Taxonomy
Lithobates virgatipes [Animal]
Temporin
Structure & Mods
ribosomal mature linear peptide [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Escherichia coli
160.0 μM
MIC
PaperJ.M. Conlon et al. / Regulatory Peptides 131 (2005) 38-45. Purification and characterization of antimicrobial peptides from the skin secretions of the carpenter frog Rana virgatipes (Ranidae, Aquarana)
RECORD: Rec_0085497 VERIFIED: YES
Provenance & Taxonomy
Rana virgatipes [Animal]
Temporin
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Amidation
C-terminal amidation
Bio-Activity Profile
Antimicrobial
Klebsiella pneumoniae KK3 9904
80 μM
MIC
PaperPurification and characterization of antimicrobial peptides from the skin secretions of the carpenter frog Rana virgatipes (Ranidae, Aquarana).
1 2 3 ... 7 NEXT LAST
Showing 5 records on this page · Page 1 of 7