Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length507 amino acids

Chemical FormulaC2570H3998N640O742S18

DescriptionStandard

        MRTKAVQVLWGCFLLWDLYVSSAQTVYPGIKARVTQRALDYGVLAGMEMTEHMVKEKNIPDLEGSESLEFLKVDYVDYNFSNIKINAFSFPNTSLAFVPGVGIKALTNHGTANISTDWEIKSPLFEDAGGADLFLSGVYFTGIVVLARNDFGHPILKLQRCYAQVSHAHVSFSGELSVLYNSFAEPMEKPILKNLNEMLCPIIMSEVEALNANLSMLEVLTKIDNYTLLDYSLISSPEITENYMELNLKGVFYPLDNLTDPPFLPVPFALPERHDSMLYVGISEFFFKSASFAYFTSGAFNVTLSLKEISSHLVQNSQGLGNVLSRIAEIYILSQPFMVRVMATEPPVISLQPGNFTLDIPASMVLLAQTENSTAEAIVSMDFVASTSVGLVILGQRLVCSLSLNRFRLSLPESNRSNIEVLRFENILSSLLHFGILPLANAKLQQGIPLPNPHKISFVNSDIEVFEGFLLISTDLKYETSLKQQLSFHGWEGLNLISGQWRGKPVA
    

Molecular Weight56310.25 Da

Isoelectric Point (pI)5.11

Net Charge (pH 7.0)-15.59

Net Charge (pH 7.4) -16.49

Charge Density (pH 7.0) -0.0308

GRAVY Index0.19

Hydrophobic Moment 0.68

Boman Index0.18

Instability Index35.70

Aliphatic Index 104.77

Aromaticity 0.1026

Extinction Coeff. Reduced 51340.00

Extinction Coeff. Oxidized 51590.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0376016 VERIFIED: NO

Provenance & Taxonomy

OrganismZalophus californianus [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria