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MYP_101924
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Basic Information
Bac8a (Bac2A variant)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Standard
8 amino acids
C57H89N17O9
Standard
Sequence
KIWVIRWR
Physicochemical Analysis
1156.42 Da
12.00
2.76
2.55
0.3449
-0.19
0.23
-0.14
59.12
133.75
0.2500
11000.00
11000.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
448.42
0.64
18.0
12.0
36.0
83.0
4.0
7.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0030601 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Staphylococcus epidermidis
4 μg/mL
MIC
PMID16041366 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16041366/
RECORD: Rec_0073312 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Pseudomonas aeruginosa
16 μg/mL
MIC
PaperHigh-throughput generation of small antibacterial peptides with improved activity. Nat Biotechnol. 2005 Aug;23(8):1008-1012. doi: 10.1038/nbt1113. PMID: 16041366. PMID16041366 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16041366/
RECORD: Rec_0107583 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Candida albicans
16 μg/mL
MIC
PMID16041366 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16041366/
RECORD: Rec_0113932 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Enterococcus faecalis
16 μg/mL
MIC
PaperHigh-throughput generation of small antibacterial peptides with improved activity. Nat Biotechnol. 2005 Aug;23(8):1008-1012. doi: 10.1038/nbt1113. PMID: 16041366. PMID16041366 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16041366/
RECORD: Rec_0126444 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
Candida albicans
16 μM
MIC
PaperHigh-throughput generation of small antibacterial peptides with improved activity PMID16041366 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16041366/
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