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MYP_101904
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Basic Information
Unnamed
Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Membrane / Ion-channel modulation ▸ Calcium channel modulation ▸ Calcium channel inhibitor
Neurological / Signaling ▸ Analgesic/opioid activity ▸ Opioid antagonist
Sensory / Food function ▸ Taste-active peptide ▸ Bitter peptide
Standard
7 amino acids
C46H59N7O12
Standard
Sequence
AYFYPEL
Physicochemical Analysis
902.00 Da
4.05
-1.20
-1.40
-0.1719
0.10
0.25
0.40
97.60
70.00
0.4286
2980.00
2980.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
306.89
0.88
10.0
11.0
23.0
65.0
4.0
6.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0046831 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antioxidant
PaperContreras M. M., S¨¢nchez-Infantes D., Sevilla M. A., Recio I., Amigo L.. Resistance of casein-derived bioactive peptides to simulated gastrointestinal digesti¨®n. Int. Dairy J., 32, 71-78, 2013.
RECORD: Rec_0075838 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
ACE-inhibitory peptide
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
ACE
6.6 μM
IC50
PaperAntihypertensive peptides: production, bioavailability and incorporation into foods. PMID21185549 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21185549/
RECORD: Rec_0081573 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
ACE-inhibitory peptide
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive
PaperBioactive Peptides: A Review
RECORD: Rec_0143864 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
alpha-S1-Casein-derived
9913
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antioxidant
Spontaneously hypertensive rats
PaperResistance of casein-derived bioactive peptides to simulated gastrointestinal digestion | Contreras, M. del Mar. et al. | DOI: 10.1016/j.idairyj.2013.05.008 Evidence URLhttps://www.uniprot.org/uniprotkb/P02662/entry
RECORD: Rec_0175847 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
alpha-S1-Casein-derived
9913
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive Opioid antagonist
PaperImplication of Opioid Receptors in the Antihypertensive Effect of a Bovine Casein Hydrolysate and αs1-Casein Derived Peptides | Sanchez-Rivera, L. et al. | DOI: 10.1021/acs.jafc.9b03872 Evidence URLhttps://www.uniprot.org/uniprotkb/P02662/entry
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