Peptide Database

Peptide Name[Phe(Me)7]neurokinin B

Function Ontology

Neurological / Signaling ▸ Receptor modulation ▸ Agonist

Neurological / Signaling ▸ Signaling peptide

Standard StatusStandard

Sequence Length10 amino acids

Chemical FormulaC59H78N12O15S2

DescriptionStandard

        DMHDFFFGLM
    

Molecular Weight1259.45 Da

Isoelectric Point (pI)4.20

Net Charge (pH 7.0)-2.15

Net Charge (pH 7.4) -2.40

Charge Density (pH 7.0) -0.2150

GRAVY Index0.54

Hydrophobic Moment 0.34

Boman Index0.42

Instability Index58.74

Aliphatic Index 39.00

Aromaticity 0.3000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 428.50

LogP -0.41

H-bond Donors 14.0

H-bond Acceptors 16.0

Rotatable Bonds 39.0

Heavy Atoms 88.0

Ring Count 4.0

Amide Bonds 9.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0366266 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

FamilyGtoPdb peptide ligand

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Receptor agonist Signaling peptide

TargetNK2 receptor (Human); NK3 receptor (Mouse); NK3 receptor (Human)

Activity1.3 nM

MethodEC50