Peptide Database

Peptide NameA20FMDV2

Function Ontology

Anticancer

Antimicrobial

Standard StatusStandard

Sequence Length21 amino acids

Chemical FormulaC103H175N33O30

DescriptionStandard

        NAYPNLRGDLQVLAQKVARTK
    

Molecular Weight2355.69 Da

Isoelectric Point (pI)10.28

Net Charge (pH 7.0)2.76

Net Charge (pH 7.4) 2.55

Charge Density (pH 7.0) 0.1313

GRAVY Index-0.62

Hydrophobic Moment 0.58

Boman Index-0.20

Instability Index28.42

Aliphatic Index 97.62

Aromaticity 0.0476

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1062.49

LogP -11.39

H-bond Donors 36.0

H-bond Acceptors 33.0

Rotatable Bonds 79.0

Heavy Atoms 166.0

Ring Count 2.0

Amide Bonds 24.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0402156 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyA20FMDV2

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermBiotinylation

Bio-Activity Profile

Function

Antimicrobial Anticancer

Half-LifeMouse serum: Degraded by over 50% in normal mouse serum within a 4 h incubation at 37 °C

PaperCardle II, Jensen MC, Pun SH, Sellers DL Optimized serum stability and specificity of an αvβ6 integrin-binding peptide for tumor targeting. J Biol Chem. 2021 Jan-Jun;296:100657. PMID:33857478 https://pubmed.ncbi.nlm.nih.gov/33857478/ PMID33857478 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33857478/