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MYP_101843
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Basic Information
Cyclic dodecapeptide
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Standard
12 amino acids
C68H122N24O13S2
Standard
Sequence
RICRIIFLRVCR
Physicochemical Analysis
1547.98 Da
11.53
3.74
3.51
0.3117
0.94
0.50
-0.17
25.22
154.17
0.0833
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
631.02
-3.27
27.0
19.0
52.0
107.0
1.0
11.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0194373 VERIFIED: YES
Provenance & Taxonomy
Ovis aries [Animal]
Cathelicidin
9940
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus
PaperBactenecin-1 Evidence URLhttps://www.uniprot.org/uniprotkb/P54230/entry
RECORD: Rec_0211326 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0274573 VERIFIED: YES
Provenance & Taxonomy
Ovis aries [Animal]
Cathelicidin
9940
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli
PaperPubMed PMID: 7498547 | PubMed PMID: 9461419 PMID7498547;9461419 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/7498547/
RECORD: Rec_0364449 VERIFIED: YES
Provenance & Taxonomy
Ovis aries [Animal]
Cathelicidin
9940
Structure & Mods
head-to-tail cyclic peptide [Cyclic]
noncanonical stereochemical modification [Modified]
Bio-Activity Profile
Antimicrobial
PapercDNA sequences of three sheep myeloid cathelicidins.
RECORD: Rec_0390540 VERIFIED: YES
Provenance & Taxonomy
Ovis aries [Animal]
Cathelicidin
9940
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus
PaperPubMed PMID: 7498547 | PubMed PMID: 9461419 PMID7498547;9461419 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/7498547/
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