Peptide Database

Peptide NameDefense protein 4

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length65 amino acids

Chemical FormulaC316H522N90O90S6

DescriptionStandard

        MYGMSVRILMMSSLSACMLVSTVTAWDFLKELEGVGQRVRDSIISAGPAIDVLKKSQGPRRWSRP
    

Molecular Weight7214.46 Da

Isoelectric Point (pI)10.01

Net Charge (pH 7.0)3.50

Net Charge (pH 7.4) 3.25

Charge Density (pH 7.0) 0.0538

GRAVY Index0.10

Hydrophobic Moment 0.61

Boman Index0.04

Instability Index67.86

Aliphatic Index 92.92

Aromaticity 0.0615

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2895.83

LogP -27.74

H-bond Donors 106.0

H-bond Acceptors 100.0

Rotatable Bonds 241.0

Heavy Atoms 502.0

Ring Count 9.0

Amide Bonds 66.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0315507 VERIFIED: NO

Provenance & Taxonomy

OrganismLonomia obliqua [Animal]

FamilyCecropin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Anti-Gram-positive Non-hemolytic Non-ribosomal

TargetGram-negative bacteria; Gram-positive bacteria

MethodQualitative functional evidence