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MYP_101787
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Basic Information
[R4,R10]C1b(3-13)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
11 amino acids
C83H122N32O12
Standard
Sequence
VWRRWRRFWRR
Physicochemical Analysis
1760.06 Da
12.00
5.73
5.52
0.5213
-2.06
1.10
-0.95
217.38
26.36
0.3636
16500.00
16500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
773.09
-3.10
33.0
18.0
54.0
127.0
7.0
10.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0389404 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
Human erythrocytes (- at NA , Human erythrocytes (1.2% Hemolysis at 500 microM, Human erythrocytes (1.56% Hemolysis at 500 microM, Human erythrocytes (1.67% Hemolysis at 500 microM
500 μM
Hemolysis
PMID27060618;31671371 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27060618/
RECORD: Rec_0400410 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Lactococcus lactis AS1.1690
3.13 μM
MIC
PMID27060618;31671371 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27060618/
RECORD: Rec_0412427 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
PaperStructure-activity analysis and biological studies of chensinin-1b analogues. Acta Biomater. 2016 Jun;37:59-68. doi: 10.1016/j.actbio.2016.04.003. PMID: 27060618. PMID27060618 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27060618/
RECORD: Rec_0412782 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Enterococcus faecium CGMCC 1.2334
3.13 μM
MIC
PMID27060618;31671371 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27060618/
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