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MYP_101762
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Basic Information
Sapecin C
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
40 amino acids
C171H279N57O51S6
Standard
Sequence
ATCDLLSGIGVQHSACALHCVFRGNRGGYCTGKGICVCRN
Physicochemical Analysis
4141.79 Da
8.69
2.91
2.53
0.0727
0.28
0.54
0.10
17.00
78.00
0.0500
1490.00
1865.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1735.02
-23.16
68.0
62.0
135.0
285.0
4.0
42.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0187870 VERIFIED: YES
Provenance & Taxonomy
Sarcophaga peregrina [Animal]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Bacillus circulans
PaperPubMed PMID: 8471044 PMID8471044 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8471044/
RECORD: Rec_0194541 VERIFIED: YES
Provenance & Taxonomy
Sarcophaga peregrina [Animal]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli
PaperPubMed PMID: 8471044 PMID8471044 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8471044/
RECORD: Rec_0216956 VERIFIED: YES
Provenance & Taxonomy
Sarcophaga peregrina [Animal]
Defensin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Klebsiella pneumoniae
PMID8471044 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8471044/
RECORD: Rec_0227723 VERIFIED: YES
Provenance & Taxonomy
Sarcophaga peregrina [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Three disulfid bonds: 3,30; 16,36; 20,38
Bio-Activity Profile
Antimicrobial
Staphylococcus aureus ATCC 6538B
0.6 μg/mL
IC50
PaperPurification, sequence and antibacterial activity of two novel sapecin homologues from Sarcophaga embryonic cells: similarity of sapecin B to charybdotoxin.
RECORD: Rec_0231191 VERIFIED: YES
Provenance & Taxonomy
Sarcophaga peregrina [Animal]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Streptococcus spps
PaperPubMed PMID: 8471044 PMID8471044 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8471044/
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