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MYP_101750
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Basic Information
Omwaprin-a (Oxywaprin; Oxywaprin-a; Snakes, reptiles, animals)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
50 amino acids
C234H380N72O72S8
Standard
Sequence
KDRPKKPGLCPPRPQKPCVKECKNDDSCPGQQKCCNYGCKDECRDPIFVG
Physicochemical Analysis
5610.48 Da
8.69
3.68
3.34
0.0737
-1.27
0.52
-0.37
51.69
27.20
0.0400
1490.00
1990.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
2329.77
-27.77
82.0
84.0
183.0
386.0
10.0
54.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0339926 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Toxic Hemolytic Anti-Gram-positive
PaperHemolytik: a database of experimentally determined hemolytic and non-hemolytic peptides PMID24174543 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24174543/
RECORD: Rec_0402101 VERIFIED: YES
Provenance & Taxonomy
Oxyuranus microlepidotus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
No hemolytic activity
Hemolysis
PMID17044815 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17044815/
RECORD: Rec_0403276 VERIFIED: YES
Provenance & Taxonomy
Oxyuranus microlepidotus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PaperAntimicrobial activity of omwaprin, a new member of the waprin family of snake venom proteins
RECORD: Rec_0417032 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial
Human erythrocytes
1000 μM
Hemolysis
Paperhttps://pubmed.ncbi.nlm.nih.gov/17044815/ PMID17044815 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17044815/
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