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MYP_101743
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Basic Information
Cecropin A (1-7) + Melittine (2-9) [A10K]
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
15 amino acids
C92H158N22O16
Standard
Sequence
KWKLFKKIGKVLKVL
Physicochemical Analysis
1828.38 Da
10.70
5.75
5.54
0.3836
0.16
0.88
0.01
-34.65
142.67
0.1333
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
642.63
1.05
23.0
22.0
67.0
130.0
3.0
14.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0166322 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Melittin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Escherichia coli BL21
0.5-1 μM
MIC
PMID18852279 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18852279/
RECORD: Rec_0210928 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Melittin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus ATCC 6538P
01-2 μM
MIC
PMID18852279 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18852279/
RECORD: Rec_0235663 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Melittin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus ATCC BAA-41
4 μM
MIC
PMID18852279 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18852279/
RECORD: Rec_0276651 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Melittin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
human red blood cells
67 % hemolysis at 64 μM
Hemolysis
PMID18852279 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18852279/
RECORD: Rec_0349062 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Melittin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Pseudomonas aeruginosa PAO1
01-2 μM
MIC
PMID18852279 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18852279/
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