Peptide Database

Peptide NameUnnamed

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Toxic

Venom / Toxin ▸ General toxin ▸ Toxin

Standard StatusStandard

Sequence Length34 amino acids

Chemical FormulaC182H267N51O51S6

DescriptionStandard

        DCLGWFKGCDPDNDKCCEGYKCNRRDKWCKYKLW
    

Molecular Weight4177.77 Da

Isoelectric Point (pI)8.29

Net Charge (pH 7.0)1.70

Net Charge (pH 7.4) 1.39

Charge Density (pH 7.0) 0.0500

GRAVY Index-1.27

Hydrophobic Moment 0.39

Boman Index-0.33

Instability Index29.35

Aliphatic Index 22.94

Aromaticity 0.1765

Extinction Coeff. Reduced 19480.00

Extinction Coeff. Oxidized 19855.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1692.56

LogP -13.93

H-bond Donors 65.0

H-bond Acceptors 59.0

Rotatable Bonds 137.0

Heavy Atoms 290.0

Ring Count 10.0

Amide Bonds 35.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0078871 VERIFIED: NO

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Toxic Cytotoxic

RECORD: Rec_0359980 VERIFIED: NO

Provenance & Taxonomy

OrganismGrammostola rosea,Grammostola spatulata [Animal]; Paraphysa scrofa,Phrixotrichus auratus [Animal]

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide2-17; 9-22; 16-29

Bio-Activity Profile

Function

Toxin

Targetpotassium channel KvAP, Aeropyrum pernix