Peptide Database

Peptide NamePyocin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length387 amino acids

Chemical FormulaC1815H2811N489O573S21

DescriptionStandard

        MGRRVITHGRGQALDGDKTTTGAKCISSLPNVKNCGKGVVRLGDRTTVCPKCSKPGTIITGELSVSYGGSPAAVDGSFVMCGCPMGTNRVIAPIGQVSISEELSQSHANNDFLPQQPPPPMPVFAKSCLRGMGCTDAGTSPEPSQNFMPVGYFMATPFSGDDQYNTQHIADNTSLNNSLAESEQHVETAATFPVGAVVFSWISGQFSTVGTWGAKSAASNIGEILVGGAGAPVAAFLVAMMPGKLNSSEQDFIDKMRLSQIADIEGTAPTRVRFAWEEQADGHMMPTGYHTDANGGWDQVPVRNMVLNSQTGNYEFTTEGIKPITIYWNPAKLDFEFKNNTGNQEPLNLPPTITVTPIPEETGGYIETYPADEKNFSDYILILPIPD
    

Molecular Weight41323.03 Da

Isoelectric Point (pI)4.86

Net Charge (pH 7.0)-14.00

Net Charge (pH 7.4) -14.72

Charge Density (pH 7.0) -0.0362

GRAVY Index-0.25

Hydrophobic Moment 0.75

Boman Index0.09

Instability Index41.47

Aliphatic Index 68.55

Aromaticity 0.0775

Extinction Coeff. Reduced 40910.00

Extinction Coeff. Oxidized 41410.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0340291 VERIFIED: YES

Provenance & Taxonomy

OrganismSalmonella enterica [Bacterium]

FamilyPyocin

Structure & Mods

Configlinear polypeptide/propeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Antibiotic Bacteriocin Non-hemolytic Non-ribosomal

TargetEscherichia coli