Peptide Database

Peptide NameUnnamed

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Hormonal / Endocrine ▸ Secretory pathway peptide ▸ Secretory granule peptide

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide precursor

Standard StatusStandard

Sequence Length91 amino acids

Chemical FormulaC510H740N132O152S

DescriptionStandard

        QYAPHHITEKRLGELLNPFYDPSQWKSSRFERKDPMDDSFLEGEEENGLTLNEKNFFPEYNYDWWEKKPFEEDVNWGYEKRNPVPKLDLKR
    

Molecular Weight11184.19 Da

Isoelectric Point (pI)4.92

Net Charge (pH 7.0)-6.04

Net Charge (pH 7.4) -6.39

Charge Density (pH 7.0) -0.0663

GRAVY Index-1.44

Hydrophobic Moment 0.62

Boman Index-0.25

Instability Index64.40

Aliphatic Index 46.04

Aromaticity 0.1648

Extinction Coeff. Reduced 29450.00

Extinction Coeff. Oxidized 29450.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4632.54

LogP -36.44

H-bond Donors 154.0

H-bond Acceptors 149.0

Rotatable Bonds 365.0

Heavy Atoms 795.0

Ring Count 29.0

Amide Bonds 99.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0080025 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/

RECORD: Rec_0105058 VERIFIED: NO

Provenance & Taxonomy

OrganismBos taurus [Animal]

FamilySecretogranin-1(476-566)

Tax ID9913

Structure & Mods

Configlinear peptide [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

N-TermPyroglutamate

Other Mods27:Phosphoserine; 28:Phosphoserine; 39:Phosphoserine; 60:Sulfotyrosine

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Half-LifeMammalian: 0.8 hour; Yeast: 10 min; E. coli: >10 hour

RECORD: Rec_0294862 VERIFIED: NO

Provenance & Taxonomy

OrganismBos taurus [Animal]

FamilyChromogranin/secretogranin

Tax ID9913

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermPyroglutamate

Other ModsSer27 Phosphoserine; Ser28 Phosphoserine; Ser39 Phosphoserine; Tyr60 Sulfotyrosine; Tyr62 Sulfotyrosine

Bio-Activity Profile

Function

Secretory granule peptide Neuropeptide precursor