Peptide Database

Peptide NameM-zodatoxin-Lt5a (M-ZDTX-Lt5a) (Latarcin-5) (Ltc-5)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Antimicrobial ▸ Antifungal

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Venom / Toxin ▸ General toxin ▸ Toxin

Standard StatusStandard

Sequence Length93 amino acids

Chemical FormulaC476H748N120O145S5

DescriptionStandard

        MKYCVVILALLVALVCITESRSTETGYAVAETLEDNDLDELQAYLEEIAEASEMEDFSNIEEARGFFGKMKEYFKKFGASFKRRFANLKKRLG
    

Molecular Weight10632.07 Da

Isoelectric Point (pI)4.89

Net Charge (pH 7.0)-4.49

Net Charge (pH 7.4) -4.78

Charge Density (pH 7.0) -0.0483

GRAVY Index-0.17

Hydrophobic Moment 0.71

Boman Index-0.00

Instability Index62.11

Aliphatic Index 85.05

Aromaticity 0.1183

Extinction Coeff. Reduced 5960.00

Extinction Coeff. Oxidized 6085.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4327.63

LogP -35.24

H-bond Donors 153.0

H-bond Acceptors 146.0

Rotatable Bonds 368.0

Heavy Atoms 746.0

Ring Count 11.0

Amide Bonds 96.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0318001 VERIFIED: YES

Provenance & Taxonomy

OrganismLachesana tarabaevi [Animal]

FamilyCationic peptide 03 (latarcin); 05 subfamily

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Antifungal Anti-Yeast Anti-Gram-negative Anti-Gram-positive Cytolytic Toxin Hemolytic

TargetA. globiformis (Gram-positive)

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