Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length101 amino acids

Chemical FormulaC491H791N137O152S12

DescriptionStandard

        MSVMKPCLMTIAILMILAQKTPGGLFRSHNGKSREPWNPCELYQGMCRNACREYEIQYLTCPDQKCCLKLSVKITSSKNVKEDYDSNSNLSVTNSSSYSHI
    

Molecular Weight11430.14 Da

Isoelectric Point (pI)8.71

Net Charge (pH 7.0)3.61

Net Charge (pH 7.4) 3.16

Charge Density (pH 7.0) 0.0357

GRAVY Index-0.39

Hydrophobic Moment 0.61

Boman Index-0.06

Instability Index47.36

Aliphatic Index 72.38

Aromaticity 0.0693

Extinction Coeff. Reduced 12950.00

Extinction Coeff. Oxidized 13325.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4695.96

LogP -52.95

H-bond Donors 169.0

H-bond Acceptors 170.0

Rotatable Bonds 383.0

Heavy Atoms 792.0

Ring Count 15.0

Amide Bonds 111.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0051674 VERIFIED: NO

Provenance & Taxonomy

OrganismPan paniscus [Animal]

FamilyDefensin

Tax ID9597

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence