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MYP_101619
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Basic Information
Bombinakinin-GAP
Antimicrobial
Cardiovascular ▸ Vascular tone modulation ▸ Vasoactive peptide
Cardiovascular ▸ Vascular tone modulation ▸ Vasodilatory activity
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Hormonal / Endocrine ▸ Hormone peptide
Metabolic ▸ Appetite and feeding regulation ▸ Feeding regulator
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Regulatory peptide ▸ Biological modulation
Regulatory peptide ▸ Biological regulation
Standard
28 amino acids
C145H220N38O40S3
Standard
Sequence
DMYEIKQYKTAHGRPPICAPGEQCPIWV
Physicochemical Analysis
3231.72 Da
6.74
-0.17
-0.46
-0.0061
-0.58
0.38
0.01
44.24
59.29
0.1071
8480.00
8605.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1231.04
-8.55
42.0
44.0
98.0
226.0
9.0
29.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0050627 VERIFIED: YES
Provenance & Taxonomy
Bombina maxima [Animal]
Bombinakinin
161274
Structure & Mods
Linear peptide with a single intramolecular disulfide-stabilized loop [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
18-24
Bio-Activity Profile
Appetite-suppressing Bradykinin receptor-modulating
PaperR. Lai et al. / Peptides 24 (2003) 199-204. Bombinakinin M gene associated peptide, a novel bioactive peptide from skin secretions of the toad Bombina maxima Evidence URLhttps://www.uniprot.org/uniprotkb/Q7T3L1/entry
RECORD: Rec_0066311 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial
PaperDADP: the database of anuran defense peptides PMID22467909 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22467909/
RECORD: Rec_0133693 VERIFIED: YES
Provenance & Taxonomy
Bombina maxima [Animal]
Bombinakinin-GAP
161274
Structure & Mods
linear peptide with reported disulfide constraint [Linear]
canonical L-amino-acid peptide [L]
Amidation
18-24
Bio-Activity Profile
Hormone Endocrine Vasoactive Vasodilator Metabolic regulation Physiological regulation Receptor modulation ACE inhibitory Feeding regulator
vitro relaxation of rat arterial smooth muscle
Mammalian: 1.1 hour; Yeast: 3 min; E. coli: >10 hour
PMID20138946 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20138946/
RECORD: Rec_0302872 VERIFIED: YES
Provenance & Taxonomy
Bombina maxima [Animal]
Bombinakinin-GAP
161274
Structure & Mods
linear peptide with reported disulfide constraint [Linear]
canonical L-amino-acid peptide [L]
Amidation
18-24
Bio-Activity Profile
Hormone Endocrine Vasoactive Vasodilator Metabolic regulation Physiological regulation Receptor modulation ACE inhibitory Feeding regulator
Mammalian: 1.1 hour; Yeast: 3 min; E. coli: >10 hour
PMID20138946 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20138946/
RECORD: Rec_0412483 VERIFIED: NO
Provenance & Taxonomy
Bombina maxima [Animal]
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
Amidation
18-24
Bio-Activity Profile
Neuropeptide