Peptide Database

Peptide NameGcg-XTEN 144

Function Ontology

Regulatory peptide ▸ Biological regulation

Standard StatusStandard

Sequence Length175 amino acids

Chemical FormulaC617H911N189O319S

DescriptionStandard

        HSQGTFTSDYSKYLDSRRAQDFVQWLMNTGGEGGSEGSEGEGSEGSGEGEGGSEGSEGEGSEGSGEGEGGSEGSEGEGGSEGSEGEGGEGSGEGEGSEGSGEGEGSGEGSEGEGGSEGGEGEGSEGGSEGEGSEGGSEGEGGEGSGEGEGGGEGSEGEGSEGSGEGEGSGEGSEG
    

Molecular Weight16111.97 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-48.02

Net Charge (pH 7.4) -48.36

Charge Density (pH 7.0) -0.2744

GRAVY Index-1.41

Hydrophobic Moment 0.66

Boman Index-0.07

Instability Index36.26

Aliphatic Index 6.69

Aromaticity 0.0286

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8480.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 8144.18

LogP -153.67

H-bond Donors 277.0

H-bond Acceptors 273.0

Rotatable Bonds 577.0

Heavy Atoms 1126.0

Ring Count 7.0

Amide Bonds 178.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0125159 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

FamilyGlucagon

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermXTEN

Bio-Activity Profile

Function

Antihyperglycemic Metabolic regulation

MethodSandwich ELISA

Half-LifeInjected subcutaneouly into cynomolgus monkeys, in vivo; 34200 s