Peptide Database

Peptide NameDefensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length95 amino acids

Chemical FormulaC449H742N140O131S8

DescriptionStandard

        MKNYVFALLVVTAVAIALPNEDKNAPMRVHLLPQKEDESLKLEVTPVKEHHRTRRFTCDLLSGAGVDHSACAAHCILRGKTGGRCNSDRVCVCRA
    

Molecular Weight10454.07 Da

Isoelectric Point (pI)8.86

Net Charge (pH 7.0)3.89

Net Charge (pH 7.4) 3.31

Charge Density (pH 7.0) 0.0409

GRAVY Index-0.14

Hydrophobic Moment 0.53

Boman Index-0.06

Instability Index29.36

Aliphatic Index 90.32

Aromaticity 0.0316

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4349.03

LogP -45.97

H-bond Donors 158.0

H-bond Acceptors 148.0

Rotatable Bonds 348.0

Heavy Atoms 728.0

Ring Count 12.0

Amide Bonds 99.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0079703 VERIFIED: NO

Provenance & Taxonomy

OrganismFormica aquilonia [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Anti-Gram-positive Non-hemolytic Non-ribosomal

TargetGram-positive bacteria

MethodQualitative functional evidence