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MYP_101517
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Basic Information
hepcidin
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Standard
20 amino acids
C92H153N35O21S9
Standard
Sequence
CRFCCRCCPRMRGCGLCCRF
Physicochemical Analysis
2374.01 Da
9.01
4.68
4.36
0.2340
0.32
0.65
-0.26
7.34
19.50
0.1000
0.00
500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
916.93
-10.58
43.0
35.0
75.0
157.0
3.0
19.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0334015 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
RECORD: Rec_0345692 VERIFIED: YES
Provenance & Taxonomy
Acanthopagrus schlegelii [Animal]
Hepcidin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Staphylococcus aureus
2.5 μM
MIC
RECORD: Rec_0356615 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 0.0%, E 20.0%, T 60.0%, C 20.0% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antibacterial Antimicrobial Antifungal Anti-Gram-positive Anti-Gram-negative
PaperYADAMP: yet another database of antimicrobial peptides PMID22325123 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22325123/
RECORD: Rec_0363234 VERIFIED: YES
Provenance & Taxonomy
Sparus aurata [Animal]
Hepcidin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
Escherichia coli DH5alpha
18.66 μM
IC50
PaperThe antimicrobial peptide hepcidin exerts an important role in the innate immunity against bacteria in the bony fish giltherad seabream
RECORD: Rec_0406489 VERIFIED: YES
Provenance & Taxonomy
Acanthopagrus schlegelii [Animal]
Hepcidin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Aspergillus niger
20 μM
MIC
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