Peptide Database

Peptide NamepAntp-PKI

Function Ontology

Anticancer

Antimicrobial

Delivery / Targeting ▸ Cell penetration ▸ Cell-penetrating peptide

Delivery / Targeting ▸ Drug delivery vehicle

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Standard StatusStandard

Sequence Length33 amino acids

Chemical FormulaC184H295N61O44S

DescriptionStandard

        RQIKIWFQNRRMKWKKTYADFIASGRTGRRNAI
    

Molecular Weight4097.76 Da

Isoelectric Point (pI)12.00

Net Charge (pH 7.0)8.76

Net Charge (pH 7.4) 8.55

Charge Density (pH 7.0) 0.2653

GRAVY Index-1.07

Hydrophobic Moment 0.51

Boman Index-0.38

Instability Index48.59

Aliphatic Index 56.36

Aromaticity 0.1515

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1792.16

LogP -16.34

H-bond Donors 67.0

H-bond Acceptors 54.0

Rotatable Bonds 141.0

Heavy Atoms 290.0

Ring Count 7.0

Amide Bonds 36.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0403143 VERIFIED: NO

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermRhodamine-labelled

C-TermNone

Bio-Activity Profile

Function

Drug Delivery Vehicle Cell-penetrating peptide

TargetCHO-K1 cells; HeLa cells; A549 cells

MethodFluorescence-based cellular uptake assay

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