Peptide Database

Peptide NameHepcidin 2

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length89 amino acids

Chemical FormulaC420H669N111O126S11

DescriptionStandard

        MKSFIAAVSLAVLLTFVCFQESSAVPVTEVHELEGTLTDDSPLPDDLKIPVTSWKTLYDIRKKREARAAGCRFCCGCCGMSGCGVCCNF
    

Molecular Weight9642.19 Da

Isoelectric Point (pI)5.69

Net Charge (pH 7.0)-1.49

Net Charge (pH 7.4) -1.91

Charge Density (pH 7.0) -0.0167

GRAVY Index0.30

Hydrophobic Moment 0.54

Boman Index0.12

Instability Index39.32

Aliphatic Index 82.13

Aromaticity 0.0787

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3753.53

LogP -37.74

H-bond Donors 140.0

H-bond Acceptors 137.0

Rotatable Bonds 313.0

Heavy Atoms 668.0

Ring Count 13.0

Amide Bonds 90.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0135228 VERIFIED: NO

Provenance & Taxonomy

OrganismOryzias melastigma [Animal]

FamilyHepcidin

Tax ID30732

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Non-hemolytic Non-ribosomal

RECORD: Rec_0352561 VERIFIED: NO