Peptide Database

Peptide NameHepcidin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length88 amino acids

Chemical FormulaC427H667N119O118S12

DescriptionStandard

        MKAFSVAVAVVVVLACMFILESTAVPFSKVLTDEVGSIDSPVGEHQQPGGESMRLPEHFRFKRQSHLSLCRWCCNCCHNKGCGFCCKF
    

Molecular Weight9740.37 Da

Isoelectric Point (pI)8.11

Net Charge (pH 7.0)1.77

Net Charge (pH 7.4) 1.20

Charge Density (pH 7.0) 0.0201

GRAVY Index0.24

Hydrophobic Moment 0.49

Boman Index0.11

Instability Index63.97

Aliphatic Index 74.09

Aromaticity 0.0909

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 6000.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3746.92

LogP -36.45

H-bond Donors 138.0

H-bond Acceptors 136.0

Rotatable Bonds 317.0

Heavy Atoms 676.0

Ring Count 17.0

Amide Bonds 92.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0247942 VERIFIED: NO

Provenance & Taxonomy

OrganismOncorhynchus tshawytscha [Animal]

FamilyHepcidin

Tax ID74940

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Non-hemolytic Non-ribosomal