Peptide Database

Peptide NamePHNX-8

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length27 amino acids

Chemical FormulaC123H219N35O37S2

DescriptionStandard

        GLMDTVKNAAKNLAGQLLDKIKCKITG
    

Molecular Weight2844.40 Da

Isoelectric Point (pI)9.52

Net Charge (pH 7.0)2.75

Net Charge (pH 7.4) 2.52

Charge Density (pH 7.0) 0.1018

GRAVY Index-0.05

Hydrophobic Moment 0.62

Boman Index0.02

Instability Index-12.73

Aliphatic Index 108.52

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1194.35

LogP -12.06

H-bond Donors 41.0

H-bond Acceptors 42.0

Rotatable Bonds 103.0

Heavy Atoms 197.0

Ring Count 0.0

Amide Bonds 29.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0184556 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyBrevinin

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative

TargetStaphylococcus aureus ATCC BAA-1718

Activity100 μg/mL

MethodMIC

RECORD: Rec_0293599 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyBrevinin

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hemolytic

TargetHuman RBC

Activity100 μg/mL

MethodHemolysis

RECORD: Rec_0308571 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyBrevinin

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative

TargetStaphylococcus aureus ATCC 33592

Activity100 μg/mL

MethodMIC

RECORD: Rec_0389806 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyBrevinin

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative

TargetEscherichia coli ATCC 4157

Activity32 μg/mL

MethodMIC

RECORD: Rec_0402913 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyBrevinin

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative

TargetEscherichia coli ATCC 51659

Activity64 μg/mL

MethodMIC