Peptide Database

Peptide NamePyocin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Enzyme / Catalytic activity ▸ Hydrolase

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length563 amino acids

Chemical FormulaC2764H4337N831O814S22

DescriptionStandard

        MTYRPDIHGRGMALSCDKTTTGAWLITSLPVPNYNVCGYGLIRKGDKTTPCPACGKPGMVAEGEARFKVIDIPIAVDGCVVHCGCPEGSNRIRAPLGQWMGAGPSPAEIAQKKQAELIAQRRAEREAEEKRREEERERNRVFAKSCLRGEGCNDAGDQREPHTNFAPMGIYQAVPQTDPVTDTEAPQRAQAVKKKKLIAPEDIPKPKKRSALWKWWNGHHEEMDYQRAVEEAERAQRARAAIAGASVLRPVAGNFAIRGTWAVVGEAATGVAGLPLAAFLIGMMPGRLNDGEQDFIDRMRAEQAREVPTRVRFTWETNSRGNPVPYGWHTPPGQDRVRVRRMEWDDRRKAYTFTTEEDPRITLIWTPDNPGIDVPYHTGNQYPPVLPNPVMVDPLPDDTGLHATTSPAPEEKDFADYILILPFPDIPPIYIYIRNNAGQVTGKGQKISGAWLVDADKGNGAPVPSQIAERMRGRTFANFDRFREAFWAEVANDADLSRQFRAHNLTNIRKGRSPFTREVDRVGGRERYEIHHIKPISEGGEVYNVDNMGITTPKRHIEIHRGK
    

Molecular Weight62937.51 Da

Isoelectric Point (pI)8.71

Net Charge (pH 7.0)6.66

Net Charge (pH 7.4) 5.50

Charge Density (pH 7.0) 0.0118

GRAVY Index-0.67

Hydrophobic Moment 0.81

Boman Index-0.11

Instability Index39.53

Aliphatic Index 66.94

Aromaticity 0.0746

Extinction Coeff. Reduced 86860.00

Extinction Coeff. Oxidized 87360.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0416483 VERIFIED: YES

Provenance & Taxonomy

OrganismEscherichia coli [Bacterium]

FamilyPyocin/Colicin

Tax ID562

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Anti-Gram-negative Hydrolase Non-hemolytic Non-ribosomal

TargetEscherichia coli