Peptide Database

Peptide NamePeginesatide

Function Ontology

Erythropoiesis-stimulating

Standard StatusStandard

Sequence Length40 amino acids

Chemical FormulaC191H302N52O54S3

DescriptionStandard

        GGLYACHMGPITNALVYQPLRSPEGSRLPQYVNALTIPGM
    

Molecular Weight4286.95 Da

Isoelectric Point (pI)8.18

Net Charge (pH 7.0)0.84

Net Charge (pH 7.4) 0.56

Charge Density (pH 7.0) 0.0209

GRAVY Index0.04

Hydrophobic Moment 0.50

Boman Index0.19

Instability Index80.03

Aliphatic Index 90.25

Aromaticity 0.0750

Extinction Coeff. Reduced 4470.00

Extinction Coeff. Oxidized 4470.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1658.02

LogP -15.65

H-bond Donors 56.0

H-bond Acceptors 59.0

Rotatable Bonds 130.0

Heavy Atoms 300.0

Ring Count 9.0

Amide Bonds 43.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0074124 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configbranched peptide architecture [Branched]

Chiralitymixed L/D amino-acid peptide [Mixed]

N-TermAcetylation

C-TermPEGylation

Disulfide6-15, 26-35

Other ModsNal, Pegylation

Bio-Activity Profile

Function

Erythropoiesis-stimulating

MethodELISA

Half-LifeMonkey blood plasma, in vitro; 122400 s