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MYP_101447
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Basic Information
VpAmp1.0
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Mycobacterium
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
19 amino acids
C103H171N21O23
Standard
Sequence
LPFFLLSLIPSAISAIKKI
Physicochemical Analysis
2071.59 Da
10.00
1.76
1.55
0.0925
1.53
0.59
0.53
29.43
174.74
0.1053
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
682.27
-0.73
23.0
25.0
66.0
147.0
4.0
18.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0362631 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct based on Vaejovis punctatus [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
as well yeasts Candida albicans
6.25 μM
MIC
PaperPeptides from the scorpion Vaejovis punctatus with broad antimicrobial activity
RECORD: Rec_0379778 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Pseudomonas aeruginosa ATCC 9027
2.5 μM
MIC
PMID26352292 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26352292/
RECORD: Rec_0406031 VERIFIED: YES
Provenance & Taxonomy
Mesomexovis punctatus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0419053 VERIFIED: YES
Provenance & Taxonomy
Vaejovis punctatus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
2.5 μM
MIC
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