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MYP_101447
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Basic Information
VpAmp1.0
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Mycobacterium
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
19 amino acids
C103H171N21O23
Standard
Sequence
LPFFLLSLIPSAISAIKKI
Physicochemical Analysis
2071.59 Da
10.00
1.76
1.55
0.0925
1.53
0.59
0.53
29.43
174.74
0.1053
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
682.27
-0.73
23.0
25.0
66.0
147.0
4.0
18.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0140976 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
Human erythrocytes (50% Hemolysis at 9.2+-0.3 microM
0.3 μM
Hemolysis
PMID26352292 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26352292/
RECORD: Rec_0143691 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Streptococcus agalactiae
2.5 μM
MIC
PMID26352292 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26352292/
RECORD: Rec_0154446 VERIFIED: YES
Provenance & Taxonomy
Vaejovis punctatus [Animal]
VpAm
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Cytotoxic Anti-mammalian cells
PaperPeptides. 2015 Sep 4;73:51-59. | https://www.ncbi.nlm.nih.gov/pubmed/26352292 PMID26352292 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26352292/
RECORD: Rec_0157097 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Candida glabrata
50.0 μM
MIC
PMID26352292 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26352292/
RECORD: Rec_0167287 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Escherichia coli ATCC 25922
24 μM
MIC
PMID26352292 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26352292/
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