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MYP_101435
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Basic Information
Chensinin-1 (3-11) [G4,7,11W, H6K]
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
9 amino acids
C71H98N22O10
Standard
Sequence
VWRKWRRFW
Physicochemical Analysis
1419.68 Da
12.00
3.73
3.52
0.4148
-1.46
0.98
-0.49
72.53
32.22
0.4444
16500.00
16500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
555.21
0.27
23.0
14.0
42.0
103.0
7.0
8.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0159469 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Enterococcus faecium CGMCC 1.2334
3.13 μM
MIC
PMID27060618 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27060618/
RECORD: Rec_0170935 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
faecalis
3.13 μM
MIC
PaperStructure-activity analysis and biological studies of chensinin-1b analogues. Acta Biomater. 2016 Jun;37:59-68. doi: 10.1016/j.actbio.2016.04.003. PMID: 27060618. PMID27060618 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27060618/
RECORD: Rec_0191903 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
Human erythrocytes (- at NA
Hemolysis
PMID27060618 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27060618/
RECORD: Rec_0200951 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Enterococcus faecalis CGMCC 1.595
3.13 μM
MIC
PMID27060618 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27060618/
RECORD: Rec_0235576 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Hemolytic
human red blood cells
500 μM
HC50
PaperStructure-activity analysis and biological studies of chensinin-1b analogues. Acta Biomater. 2016 Jun;37:59-68. doi: 10.1016/j.actbio.2016.04.003. PMID: 27060618. PMID27060618 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27060618/
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