Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length200 amino acids

Chemical FormulaC1017H1537N229O309S8

DescriptionStandard

        QIDDLAEVDYSLSSLPAVFRPFIDLDLKGVAFPAGNYTDSPYVPASFTIPDQSDSMLYLAFSEYFFQTSSFAYYTTGAFNITIAEEVKSGNSFVFSLFFFLQTCSYFNINTEIFGTIIPEVAKYSVTPNPVMLKLMATEIPIISLEQDSFTVEIQGSMEVLAVLPDSTTQSLFTMNIAANTSISLNVFDQKLMGSLCLNR
    

Molecular Weight22171.95 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-14.23

Net Charge (pH 7.4) -14.51

Charge Density (pH 7.0) -0.0712

GRAVY Index0.31

Hydrophobic Moment 0.60

Boman Index0.24

Instability Index44.22

Aliphatic Index 92.15

Aromaticity 0.1400

Extinction Coeff. Reduced 13410.00

Extinction Coeff. Oxidized 13535.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 8541.39

LogP -104.59

H-bond Donors 290.0

H-bond Acceptors 303.0

Rotatable Bonds 708.0

Heavy Atoms 1563.0

Ring Count 39.0

Amide Bonds 217.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0246142 VERIFIED: NO

Provenance & Taxonomy

OrganismCorvus moneduloides [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria