Peptide Database

Peptide NameSLAY-screened peptide P3684

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length20 amino acids

Chemical FormulaC113H161N25O30S

DescriptionStandard

        DCDPYLPSTPYPLTLHHWII
    

Molecular Weight2381.70 Da

Isoelectric Point (pI)5.05

Net Charge (pH 7.0)-2.08

Net Charge (pH 7.4) -2.40

Charge Density (pH 7.0) -0.1038

GRAVY Index-0.13

Hydrophobic Moment 0.20

Boman Index0.26

Instability Index43.12

Aliphatic Index 97.50

Aromaticity 0.1500

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8480.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 829.96

LogP -2.95

H-bond Donors 28.0

H-bond Acceptors 31.0

Rotatable Bonds 63.0

Heavy Atoms 169.0

Ring Count 10.0

Amide Bonds 19.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0138293 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/