Peptide Database

Peptide NameHeteroscorpine-1 (HS-1)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Venom / Toxin ▸ General toxin ▸ Toxin

Standard StatusStandard

Sequence Length95 amino acids

Chemical FormulaC446H730N124O131S10

DescriptionStandard

        MNSKLTALIFLGLVAIASCGWINEEKIQKKIDEKIGNNILGGMAKAVVHKLAKGEFQCVANIDTMGNCETHCQKTSGEKGFCHGTKCKCGKPLSY
    

Molecular Weight10245.97 Da

Isoelectric Point (pI)8.88

Net Charge (pH 7.0)4.70

Net Charge (pH 7.4) 4.20

Charge Density (pH 7.0) 0.0494

GRAVY Index-0.12

Hydrophobic Moment 0.59

Boman Index0.06

Instability Index20.29

Aliphatic Index 81.16

Aromaticity 0.0526

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7365.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4118.53

LogP -42.32

H-bond Donors 146.0

H-bond Acceptors 149.0

Rotatable Bonds 358.0

Heavy Atoms 711.0

Ring Count 10.0

Amide Bonds 103.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0196255 VERIFIED: YES

Provenance & Taxonomy

OrganismHeterometrus laoticus [Animal]

FamilyLong chain scorpion toxin; Class 3 subfamily

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Anti-Gram-negative Anti-Gram-positive Toxin Non-hemolytic

TargetK. pneumoniae (Gram-negative)

RECORD: Rec_0369945 VERIFIED: YES