Peptide Database

Peptide NameHolotricin-2

Function Ontology

Antimicrobial

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length127 amino acids

Chemical FormulaC626H977N175O187S4

DescriptionStandard

        MMKLVIALCLIGISAAYVVPVYYEIYPEDATFDEADIEPQLSPAELHHGSIRERRSLQPGAPSFPMPGSQLPTSVSGNVEKQGRNTIATIDAQHKTDRYDVRGTWTKVVDGPGRSKPNFRIGGSYRW
    

Molecular Weight14074.77 Da

Isoelectric Point (pI)6.83

Net Charge (pH 7.0)-0.23

Net Charge (pH 7.4) -0.65

Charge Density (pH 7.0) -0.0018

GRAVY Index-0.42

Hydrophobic Moment 0.62

Boman Index-0.01

Instability Index56.14

Aliphatic Index 76.77

Aromaticity 0.0866

Extinction Coeff. Reduced 19940.00

Extinction Coeff. Oxidized 19940.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5770.26

LogP -58.30

H-bond Donors 200.0

H-bond Acceptors 194.0

Rotatable Bonds 450.0

Heavy Atoms 992.0

Ring Count 27.0

Amide Bonds 134.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0232875 VERIFIED: YES

Provenance & Taxonomy

OrganismHolotrichia diomphalia [Animal]

FamilyColeoptericin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Non-hemolytic