‹ ›
MYP_101317
← PREVIOUS NEXT → BACK
Basic Information
Antimicrobial peptide Ac-AMP2
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Enzyme modulation ▸ Enzyme inhibition ▸ Amylase inhibition ▸ Alpha-amylase inhibitory
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity
Standard
30 amino acids
C130H206N42O38S7
Standard
Sequence
VGECVRGRCPSGMCCSQFGYCGKGPKYCGR
Physicochemical Analysis
3189.74 Da
8.92
3.67
3.37
0.1224
-0.35
0.53
-0.09
21.88
19.33
0.1000
2980.00
3355.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1288.69
-17.16
52.0
49.0
102.0
217.0
5.0
30.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0121851 VERIFIED: YES
Provenance & Taxonomy
Amaranthus caudatus [Plant]
Defensin
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Disulfide bond(s) reported
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Antifungal
Colletotrichum lindemuthianum
8 μg/mL
IC50
PaperPubMed PMID: 1567877 | PubMed PMID: 8627629 | PubMed PMID: 9176817 PMID1567877;8627629;9176817 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/1567877/
RECORD: Rec_0158108 VERIFIED: YES
Provenance & Taxonomy
Amaranthus hypochondriacus [Plant]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0163129 VERIFIED: YES
Provenance & Taxonomy
Foxtail amaranth [Plant]; Insecta [Animal]
33090; 50557
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Acetylation
Bio-Activity Profile
Antimicrobial
PMID22705624 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22705624/
RECORD: Rec_0180375 VERIFIED: YES
Provenance & Taxonomy
Amaranthus caudatus [Plant]; Amaranthus hypochondriacus [Plant]
Hevein
28502
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
disulfide bond reported, sites not specified
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Alpha-amylase Inhibitory
Sarcina lutea
250 μg/mL
IC50
PaperPubMed PMID 1567877 | PubMed PMID 1238788 | PubMed PMID 9000000 PMID1567877;1238788;9000000;15678771;23878;89000 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/1567877/
RECORD: Rec_0188190 VERIFIED: YES
Provenance & Taxonomy
Amaranthus caudatus [Plant]; Amaranthus hypochondriacus [Plant]
Hevein
28502
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
disulfide bond reported, sites not specified
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Alpha-amylase Inhibitory
Alternaria brassicola
7 μg/mL
IC50
PaperPubMed PMID 1567877 | PubMed PMID 1238788 | PubMed PMID 9000000 PMID1567877;1238788;9000000;15678771;23878;89000 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/1567877/
FIRST PREV 1 2 3 4 ... 6 NEXT LAST
Showing 5 records on this page · Page 2 of 6