Peptide Database

Peptide NameEndolysin (EC 3.5.1.28) (N-acetylmuramoyl-L-alanine amidase)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Bacteriolytic activity ▸ Bacteriolytic enzyme

Enzyme / Catalytic activity ▸ Hydrolase

Enzyme / Catalytic activity ▸ Hydrolase ▸ Nuclease

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length151 amino acids

Chemical FormulaC753H1179N219O215S5

DescriptionStandard

        MAKVQFKPRATTEAIFVHCSATKPSQNIGVREIRQWHKEQGWLDVGYHFIIKRDGTVEAGRDELAVGSHVKGYNHNSVGVCLVGGIDDKGKFDANFTPAQMQALRSLLVTLLAKYEGSILRAHHDVAPKACPSFDLKRWWEKNELVTSDRG
    

Molecular Weight16900.08 Da

Isoelectric Point (pI)9.03

Net Charge (pH 7.0)4.10

Net Charge (pH 7.4) 3.44

Charge Density (pH 7.0) 0.0271

GRAVY Index-0.40

Hydrophobic Moment 0.75

Boman Index-0.03

Instability Index38.01

Aliphatic Index 80.07

Aromaticity 0.0861

Extinction Coeff. Reduced 26470.00

Extinction Coeff. Oxidized 26595.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6989.86

LogP -67.59

H-bond Donors 246.0

H-bond Acceptors 231.0

Rotatable Bonds 563.0

Heavy Atoms 1192.0

Ring Count 29.0

Amide Bonds 161.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0420223 VERIFIED: YES

Provenance & Taxonomy

OrganismYersinia phage phiYeO3-12 [Virus]

FamilyN-acetylmuramoyl-L-alanine amidase 2

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Endonuclease Exonuclease Helicase Hydrolase Nuclease Cytolytic Non-hemolytic

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