Peptide Database

Peptide NameTemporin-SHe

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Fungicidal activity

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Standard StatusStandard

Sequence Length64 amino acids

Chemical FormulaC322H523N83O97S2

DescriptionStandard

        MFTLKKSLLLLFFLGTINLSLCEQERDAEEERRDGTDESDVEVEKRFLPALAGIAGLLGKIFGK
    

Molecular Weight7173.23 Da

Isoelectric Point (pI)4.82

Net Charge (pH 7.0)-3.49

Net Charge (pH 7.4) -3.74

Charge Density (pH 7.0) -0.0545

GRAVY Index-0.03

Hydrophobic Moment 0.51

Boman Index0.03

Instability Index39.84

Aliphatic Index 106.72

Aromaticity 0.0781

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2920.69

LogP -23.01

H-bond Donors 102.0

H-bond Acceptors 96.0

Rotatable Bonds 251.0

Heavy Atoms 504.0

Ring Count 6.0

Amide Bonds 65.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0215413 VERIFIED: NO

Provenance & Taxonomy

OrganismPelophylax saharicus [Animal]

FamilyTemporin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Amphibian defense peptide Antibiotic Antimicrobial Antifungal Fungicide Cytolytic Hemolytic Non-ribosomal

TargetLeishmania, Trypanosoma

MethodQualitative functional evidence