Peptide Database

Peptide NameBovine Beta-defensin 2

Function Ontology

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Standard StatusStandard

Sequence Length38 amino acids

Chemical FormulaC176H307N71O45S7

DescriptionStandard

        VRNRLSCHRNKGVCVPSRCPRHMRQIGTCRGPPVKCCR
    

Molecular Weight4362.22 Da

Isoelectric Point (pI)11.22

Net Charge (pH 7.0)9.85

Net Charge (pH 7.4) 9.44

Charge Density (pH 7.0) 0.2591

GRAVY Index-0.75

Hydrophobic Moment 0.73

Boman Index-0.42

Instability Index66.76

Aliphatic Index 51.05

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 375.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1899.42

LogP -25.02

H-bond Donors 75.0

H-bond Acceptors 64.0

Rotatable Bonds 142.0

Heavy Atoms 299.0

Ring Count 6.0

Amide Bonds 40.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0049590 VERIFIED: YES

Provenance & Taxonomy

OrganismOvis aries [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

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TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)