Peptide Database

Peptide NameHepcidin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory

Hormonal / Endocrine ▸ Hormone peptide

Immunology ▸ Immune modulation ▸ Immunomodulatory activity

Regulatory peptide ▸ Biological modulation

Regulatory peptide ▸ Biological regulation

Standard StatusStandard

Sequence Length25 amino acids

Chemical FormulaC111H177N31O35S8

DescriptionStandard

        DTNFPICIFCCKCCNNSQCGICCKT
    

Molecular Weight2762.30 Da

Isoelectric Point (pI)7.70

Net Charge (pH 7.0)0.68

Net Charge (pH 7.4) 0.36

Charge Density (pH 7.0) 0.0272

GRAVY Index0.38

Hydrophobic Moment 0.32

Boman Index0.08

Instability Index0.56

Aliphatic Index 46.80

Aromaticity 0.0800

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1075.32

LogP -14.39

H-bond Donors 43.0

H-bond Acceptors 44.0

Rotatable Bonds 88.0

Heavy Atoms 185.0

Ring Count 3.0

Amide Bonds 28.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0307555 VERIFIED: YES

Provenance & Taxonomy

OrganismMus musculus [Animal]

FamilyHepcidin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

-

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)

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