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MYP_101260
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Basic Information
Hepcidin
Antimicrobial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Hormonal / Endocrine ▸ Hormone peptide
Immunology ▸ Immune modulation ▸ Immunomodulatory activity
Regulatory peptide ▸ Biological modulation
Regulatory peptide ▸ Biological regulation
Standard
25 amino acids
C111H177N31O35S8
Standard
Sequence
DTNFPICIFCCKCCNNSQCGICCKT
Physicochemical Analysis
2762.30 Da
7.70
0.68
0.36
0.0272
0.38
0.32
0.08
0.56
46.80
0.0800
0.00
500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1075.32
-14.39
43.0
44.0
88.0
185.0
3.0
28.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0077226 VERIFIED: YES
Provenance & Taxonomy
Mus musculus [Animal]
Hepcidin
10090
Structure & Mods
disulfide-constrained peptide [Cyclic]
canonical L-amino-acid peptide [L]
7-23; 10-13; 11-19; 14-22
Bio-Activity Profile
Antimicrobial Anti-Gram-negative Hormone Endocrine Growth regulation Development regulation Receptor modulation Immunomodulatory ACE inhibitory
iron-exporting cells
Mammalian: 1.1 hour; Yeast: 3 min; E. coli: >10 hour
PaperSource-linked PubMed record(s) for Hepcidin (Mus musculus): PMID 24880340 PMID24880340 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24880340/
RECORD: Rec_0157817 VERIFIED: YES
Provenance & Taxonomy
Mus musculus [Animal]
Hepcidin
10090
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PaperHepcidin Evidence URLhttps://www.uniprot.org/uniprotkb/Q9EQ21/entry
RECORD: Rec_0186510 VERIFIED: YES
Provenance & Taxonomy
Mus musculus [Animal]
Hepcidin
10090
Structure & Mods
disulfide-constrained peptide [Cyclic]
canonical L-amino-acid peptide [L]
7-23; 10-13; 11-19; 14-22
Bio-Activity Profile
Antimicrobial Anti-Gram-negative Hormone Endocrine Growth regulation Development regulation Receptor modulation Immunomodulatory ACE inhibitory
Mammalian: 1.1 hour; Yeast: 3 min; E. coli: >10 hour
PaperSource-linked PubMed record(s) for Hepcidin (Mus musculus): PMID 24880340 PMID24880340 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24880340/
RECORD: Rec_0196364 VERIFIED: YES
Provenance & Taxonomy
Mus musculus [Animal]
Hepcidin
10090
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Disulfide bond(s) reported
Bio-Activity Profile
Antimicrobial
PaperPubMed PMID: 11113132 | PubMed PMID: 11447267 PMID11113132;11447267 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11113132/
RECORD: Rec_0225145 VERIFIED: NO
Provenance & Taxonomy
Mus musculus [Animal]
Hepcidin
10090
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
7-13; 10-23; 11-22; 14-19
Bio-Activity Profile
Antimicrobial
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