Peptide Database

Peptide NameD1

Function Ontology

Anticancer

Antimicrobial

Delivery / Targeting ▸ Cell penetration ▸ Cell-penetrating peptide

Delivery / Targeting ▸ Drug delivery vehicle

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Standard StatusStandard

Sequence Length38 amino acids

Chemical FormulaC227H434N86O40

DescriptionStandard

        RLRLRLRLRLRLRLRLKRLKRLKRLKRLKKKKKKKGYK
    

Molecular Weight5008.43 Da

Isoelectric Point (pI)12.00

Net Charge (pH 7.0)23.75

Net Charge (pH 7.4) 23.52

Charge Density (pH 7.0) 0.6249

GRAVY Index-1.50

Hydrophobic Moment 0.61

Boman Index-0.92

Instability Index63.89

Aliphatic Index 123.16

Aromaticity 0.0263

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2215.29

LogP -13.82

H-bond Donors 88.0

H-bond Acceptors 64.0

Rotatable Bonds 197.0

Heavy Atoms 353.0

Ring Count 1.0

Amide Bonds 37.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0080658 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyCell-penetrating peptide dendrimer

Tax ID32630

Structure & Mods

Configbranched peptide dendrimer [Branched]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermAmidation

Bio-Activity Profile

Function

Low hemolytic activity Low cytotoxicity Cell-penetrating peptide Cargo delivery

TargetHeLa cells

MethodCellular uptake and cargo-internalization assay

RECORD: Rec_0129437 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyCell-penetrating peptide dendrimer

Tax ID32630

Structure & Mods

Configbranched peptide dendrimer [Branched]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermAmidation

Bio-Activity Profile

Function

Low hemolytic activity Low cytotoxicity Cell-penetrating peptide Cargo delivery

TargetHeLa cells

MethodCellular uptake and cargo-internalization assay

RECORD: Rec_0184481 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyCell-penetrating peptide dendrimer

Tax ID32630

Structure & Mods

Configbranched peptide dendrimer [Branched]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermAmidation

Bio-Activity Profile

Function

Low hemolytic activity Low cytotoxicity Cell-penetrating peptide Cargo delivery

TargetHeLa cells

MethodCellular uptake and cargo-internalization assay

RECORD: Rec_0400833 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyCell-penetrating peptide dendrimer

Tax ID32630

Structure & Mods

Configbranched peptide dendrimer [Branched]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermAmidation

Bio-Activity Profile

Function

Low hemolytic activity Low cytotoxicity Cell-penetrating peptide Cargo delivery

TargetHeLa cells

MethodCellular uptake and cargo-internalization assay