Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length437 amino acids

Chemical FormulaC2171H3505N555O612S20

DescriptionStandard

        MSPCCLLALLAVISLTLAASPGVKVKLTDKGIEYGKQIGMASLQQKLKTIKVPDLSGTEKVPPIGKVKYSLTGMTIVNLGLPKSALVLMPGTGVRLAITNAFINLHGNWRVRYFRFIQDRGSFDLTVNGLTITADIAIKSDETGRPTVSTVNCVANVGSASIKFHGGASWLYNLFKSYIDKALRSALQKQICPLVADVITDMNPHLKTFNVLAKVDQYAEIEYSMVTSPTISKSSIEFSLKGEFYNIGKHREPPFSPTPFSLPPQDNNMLYIGVSSFTPNSAGFVYNNAGALSLYVTDDMVINILLRIKERLCVLFQIAKRFPGMMMKLLVKTVKEPTISLEPNNVTVQASGTVTAYAIQPNTTLSPLFVLNMVSQSVQPLDNIFLMVLKVVVIPKVNARLEKGFPLPTIGKMNLINTQLQVLKDYMLIGTDVQFTG
    

Molecular Weight47814.70 Da

Isoelectric Point (pI)9.48

Net Charge (pH 7.0)14.81

Net Charge (pH 7.4) 14.22

Charge Density (pH 7.0) 0.0339

GRAVY Index0.21

Hydrophobic Moment 0.70

Boman Index0.16

Instability Index33.24

Aliphatic Index 105.68

Aromaticity 0.0778

Extinction Coeff. Reduced 30370.00

Extinction Coeff. Oxidized 30620.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0172437 VERIFIED: NO

Provenance & Taxonomy

OrganismOncorhynchus kisutch [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria

MethodQualitative functional evidence