Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length145 amino acids

Chemical FormulaC715H1142N192O221S12

DescriptionStandard

        MNLLMLTFVICALLTQVTKGSFAPQKCWKNNIGYCRRRCLDTERYILLCRNKLSCCISIIISHEYTQRPAFPVIHMEDITFDDSYVDSFTGSPVSRLNDLVTFRTTNSGETVTLETNTFETTMTPPKATTSKTTMPSSPTALTNN
    

Molecular Weight16348.65 Da

Isoelectric Point (pI)8.18

Net Charge (pH 7.0)1.62

Net Charge (pH 7.4) 1.17

Charge Density (pH 7.0) 0.0112

GRAVY Index-0.15

Hydrophobic Moment 0.60

Boman Index0.02

Instability Index50.75

Aliphatic Index 76.62

Aromaticity 0.0828

Extinction Coeff. Reduced 11460.00

Extinction Coeff. Oxidized 11835.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6661.52

LogP -74.83

H-bond Donors 241.0

H-bond Acceptors 237.0

Rotatable Bonds 530.0

Heavy Atoms 1140.0

Ring Count 23.0

Amide Bonds 156.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0020816 VERIFIED: NO

Provenance & Taxonomy

OrganismAotus nancymaae [Animal]

FamilyDefensin

Tax ID37293

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence