Peptide Database

Peptide NameLipotropin beta

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Neurological / Signaling ▸ Neuromodulation

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide precursor

Standard StatusStandard

Sequence Length91 amino acids

Chemical FormulaC438H690N120O133S3

DescriptionStandard

        ELAGERPEPALGPEGAAEGMAALADLEYGLVAKAEVAEKKDDGPYKMEHFRWGSPGKDKRYGGFMTSEKSQTPLVTLFKNAIIKNAHKKGQ
    

Molecular Weight9861.08 Da

Isoelectric Point (pI)7.03

Net Charge (pH 7.0)0.03

Net Charge (pH 7.4) -0.28

Charge Density (pH 7.0) 0.0003

GRAVY Index-0.72

Hydrophobic Moment 0.49

Boman Index-0.06

Instability Index31.83

Aliphatic Index 61.32

Aromaticity 0.0769

Extinction Coeff. Reduced 9970.00

Extinction Coeff. Oxidized 9970.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4051.28

LogP -38.72

H-bond Donors 136.0

H-bond Acceptors 138.0

Rotatable Bonds 333.0

Heavy Atoms 694.0

Ring Count 16.0

Amide Bonds 94.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0163457 VERIFIED: NO

Provenance & Taxonomy

OrganismNeovison vison [Animal]

FamilyPOMC

Tax ID452646

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hormone precursor Neuropeptide precursor

RECORD: Rec_0189637 VERIFIED: YES

Provenance & Taxonomy

OrganismNeogale vison [Animal]

FamilyLipotropin

Tax ID452646

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hormone Endocrine Neuropeptide Neuromodulator

Half-LifeMammalian: 1 hour; Yeast: 30 min; E. coli: >10 hour

RECORD: Rec_0310871 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/