Peptide Database

Peptide NameCYO8_VIOOD

Function Ontology

Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive

Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory

Neurological / Signaling ▸ Signaling peptide

Other / Curated residual function label ▸ Generic enzyme inhibition annotation

Standard StatusStandard

Sequence Length118 amino acids

Chemical FormulaC551H898N140O167S10

DescriptionStandard

        DEQTISALTGKTIISNPVLEEALLTHSNSINALGGTLPCGESCVWIPCISMEMKNMVVGLFLIAAFALPALATNFEKDFITHETVQAILKKVGPSSNGMLSVVGCSCKSKVCYKNSLA
    

Molecular Weight12476.51 Da

Isoelectric Point (pI)6.09

Net Charge (pH 7.0)-1.11

Net Charge (pH 7.4) -1.53

Charge Density (pH 7.0) -0.0094

GRAVY Index0.43

Hydrophobic Moment 0.55

Boman Index0.23

Instability Index19.96

Aliphatic Index 103.31

Aromaticity 0.0508

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7365.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4853.72

LogP -49.37

H-bond Donors 170.0

H-bond Acceptors 178.0

Rotatable Bonds 414.0

Heavy Atoms 868.0

Ring Count 14.0

Amide Bonds 126.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0370991 VERIFIED: YES

Provenance & Taxonomy

OrganismViola odorata [Plant]

FamilyCyclotide

Tax ID97441

Structure & Mods

Confighead-to-tail cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidedisulfide bond reported, sites not specified

Bio-Activity Profile

Function

Signaling Enzyme inhibitory ACE inhibitory Antihypertensive

TargetAngiotensin-converting enzyme