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MYP_100974
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Basic Information
Gm defensin-like peptide (Insects, animals)
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Antimicrobial ▸ Antifungal ▸ Anti-Candida
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
44 amino acids
C210H308N62O66S6
Standard
Sequence
DKLIGSCVWGATNYTSDCNAECKRRGYKGGHCGSFWNVNCWCEE
Physicochemical Analysis
4949.46 Da
6.73
-0.20
-0.56
-0.0046
-0.65
0.55
-0.07
44.35
35.45
0.1364
19480.00
19855.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
2093.00
-24.97
80.0
73.0
159.0
344.0
10.0
47.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0060723 VERIFIED: YES
Provenance & Taxonomy
Galleria mellonella [Animal]
Defensin
7130
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
7-32, 18-40, 22-42
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Antifungal
Trichoderma harzianum
2.9 μM
MIC
PMID17194500 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17194500/
RECORD: Rec_0065442 VERIFIED: YES
Provenance & Taxonomy
Galleria mellonella [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive
S. lutea
1.4-1.9 μM
MIC
PMID17194500 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17194500/
RECORD: Rec_0073204 VERIFIED: YES
Provenance & Taxonomy
Galleria mellonella [Animal]
Defensin
7130
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
7-32, 18-40, 22-42
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Antifungal
fructus
2.9 μM
MIC
PMID17194500 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17194500/
RECORD: Rec_0083244 VERIFIED: YES
Provenance & Taxonomy
Galleria mellonella [Animal]
Defensin
7137
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
filamentous fungi A. niger and T. harzianum
2.9 μM
MIC
PaperPurification and characterization of eight peptides from Galleria mellonella immune hemolymph
RECORD: Rec_0088716 VERIFIED: YES
Provenance & Taxonomy
Galleria mellonella [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive
T. harzianum
1.4-2.9 μM
MIC
PMID17194500 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17194500/
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