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MYP_100955
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Basic Information
TBD-1 (Turtle beta-defensin 1; Reptiles, animals)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive ▸ Anti-Staphylococcus aureus
Antimicrobial ▸ Antibiotic activity
Antimicrobial ▸ Antifungal
Antimicrobial ▸ Antifungal ▸ Anti-Candida
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
40 amino acids
C193H311N65O51S6
Standard
Sequence
YDLSKNCRLRGGICYIGKCPRRFFRSGSCSRGNVCCLRFG
Physicochemical Analysis
4550.33 Da
9.86
7.70
7.40
0.1924
-0.29
0.93
-0.20
63.07
56.00
0.1250
2980.00
3355.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1919.63
-23.01
78.0
65.0
151.0
315.0
6.0
41.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0279774 VERIFIED: NO
Provenance & Taxonomy
European pond [Animal]; Animalia [Animal]
33208; 33208
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
RECORD: Rec_0283912 VERIFIED: YES
Provenance & Taxonomy
Emys orbicularis [Animal]
Defensin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Escherichia coli
PMID19253295 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19253295/
RECORD: Rec_0335890 VERIFIED: YES
Provenance & Taxonomy
Emys orbicularis [Plant]
Defensin
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
7-35, 14-29, 19-36
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Escherichia coli ML35p
0.65 μM
MIC
PMID19253295 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19253295/
RECORD: Rec_0363520 VERIFIED: YES
Provenance & Taxonomy
Emys orbicularis [Animal]
Defensin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Listeria monocytogenes
PMID19253295 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19253295/
RECORD: Rec_0412798 VERIFIED: YES
Provenance & Taxonomy
Emys orbicularis [other]
Beta-defensin; Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibiotic Defensin Anti-MRSA Antifungal Anti-Candida Hemolytic
No Target Organism Found
PMID19253295 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19253295/
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