Peptide Database

Peptide NameDefensin-A1 (DefA1) (OaDefA1)

Function Ontology

Antimicrobial

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length98 amino acids

Chemical FormulaC444H732N126O148S8

DescriptionStandard

        MQTLSFLLALLFLVAQTPAQPTGEGEKGGTIQEPEATEAQDTAAVLMAAGAADGDDSDTKQLDTTFCRCRVSCNILEKYSGKCELSGRTARICCRKIK
    

Molecular Weight10459.84 Da

Isoelectric Point (pI)5.04

Net Charge (pH 7.0)-2.54

Net Charge (pH 7.4) -2.87

Charge Density (pH 7.0) -0.0259

GRAVY Index-0.19

Hydrophobic Moment 0.79

Boman Index-0.02

Instability Index27.55

Aliphatic Index 76.84

Aromaticity 0.0408

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4435.48

LogP -53.16

H-bond Donors 159.0

H-bond Acceptors 154.0

Rotatable Bonds 355.0

Heavy Atoms 726.0

Ring Count 7.0

Amide Bonds 104.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0313710 VERIFIED: YES

Provenance & Taxonomy

OrganismOrnithorhynchus anatinus [Animal]

FamilyAlpha-defensin; Defensin

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidedisulfide bond; sites not specified

Bio-Activity Profile

Function

Antimicrobial Defensin Non-hemolytic