Peptide Database

Peptide NameCircular bacteriocin; circularin A uberolysin family

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length105 amino acids

Chemical FormulaC509H826N126O131S2

DescriptionStandard

        MANRLNVIKVPVLLTATAIIMLGYFALLGTLPIADLAKEFGVPSAVGSVVAWYLDLGAAASIIIGLLTGFLSGGLGLIAAAGRETLKAFLLAELRNRGTKAFVAW
    

Molecular Weight10870.90 Da

Isoelectric Point (pI)9.69

Net Charge (pH 7.0)2.50

Net Charge (pH 7.4) 2.27

Charge Density (pH 7.0) 0.0239

GRAVY Index1.04

Hydrophobic Moment 0.49

Boman Index0.41

Instability Index15.54

Aliphatic Index 139.52

Aromaticity 0.0857

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 13980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4005.14

LogP -25.18

H-bond Donors 141.0

H-bond Acceptors 136.0

Rotatable Bonds 353.0

Heavy Atoms 768.0

Ring Count 14.0

Amide Bonds 107.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0324200 VERIFIED: NO

Provenance & Taxonomy

OrganismNeobacillus thermocopriae [Bacterium]

FamilyCircular bacteriocin

Structure & Mods

Confighead-to-tail cyclic bacteriocin scaffold [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Bacteriocin Non-hemolytic Non-ribosomal