Peptide Database

Peptide NameInsulin-1 A chain

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Regulatory peptide ▸ Biological regulation

Standard StatusStandard

Sequence Length21 amino acids

Chemical FormulaC102H155N29O33S5

DescriptionStandard

        GIVEQCCHRPCSMFELENYCN
    

Molecular Weight2475.82 Da

Isoelectric Point (pI)4.75

Net Charge (pH 7.0)-2.18

Net Charge (pH 7.4) -2.50

Charge Density (pH 7.0) -0.1040

GRAVY Index-0.27

Hydrophobic Moment 0.45

Boman Index-0.02

Instability Index28.12

Aliphatic Index 50.95

Aromaticity 0.0952

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1740.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1008.74

LogP -10.52

H-bond Donors 37.0

H-bond Acceptors 37.0

Rotatable Bonds 79.0

Heavy Atoms 169.0

Ring Count 4.0

Amide Bonds 23.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0117569 VERIFIED: NO

Provenance & Taxonomy

OrganismThunnus orientalis [Animal]

FamilyInsulin

Tax ID8238

Structure & Mods

Configdisulfide-constrained peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide6-11

Bio-Activity Profile

Function

Hormone Endocrine Metabolic regulation Physiological regulation

Half-LifeMammalian: 30 hour; Yeast: >20 hour; E. coli: >10 hour